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Real-world persistence is low: about half discontinue within a year and roughly three-quarters within two years , often due to cost or side effectsraising the risk of rebound weight and lost health gains (Scientific American on discontinuation rates)

Clinical assessment should include a thorough history and examination to exclude other causes of persistent hiccups, such as gastro-oesophageal reflux disease (GORD), gastric distension, central nervous system pathology, metabolic disturbances, or medication interactions

Staying active is another good strategy, as physical activity helps improve circulation and generate body heat

At Neuvo Medical Spa, we provide ongoing support and monitoring to ensure that your weight loss journey stays on track

Studies have shown that GLP-1 drugs can reduce lean mass, but the results are mixed

Contrave works on brain chemistry instead, produces a more modest 5 to 8 percent average, but comes without the GI side effects, injection requirement, or cost barriers that keep some patients away from GLP-1s